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A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides
systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviews
the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three
main classes of xenobiotics: drugs, natural products, environmental pollutants. The part on drugs includes more than 300 substances from
five major therapeutic groups (central nervous system, cardiovascular system, cancer, infection, and pain) as well as most drugs of abuse

including nicotine, alcohol and "designer" drugs. Selected, well-documented case studies from the most important xenobiotics classes illustrate general principles of metabolism, making this equally useful for teaching courses on pharmacology, drug metabolism or molecular
toxicology.
Of particular interest, and unique to this volume is the inclusion of a wide range of additional xenobiotic compounds, including food supplements, herbal preparations, and agrochemicals.

• Sales Rank: #1088307 in Books
• Published on: 2012-05-29
• Original language: English
• Number of items: 1
• Dimensions: 9.80" h x 1.50" w x 7.00" l, 3.35 pounds
• Binding: Hardcover
• 753 pages

Review

“Overall therefore, a book which can be read in its own right for the first half and then a valuable source of reference for the second half.  A useful tome to have on the bookshelf for anyone in the field.”  (British Toxicology Society, 1 July 2013)

From the Back Cover
A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviews the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three main classes of xenobiotics: drugs, natural products, environmental pollutants. The part on drugs includes more than 300 substances from five major therapeutic groups (central nervous system, cardiovascular system, cancer, infection, and pain) as well as most drugs of abuse including nicotine, alcohol and "designer" drugs. Selected, well-documented case studies from the most important xenobiotics classes illustrate general principles of metabolism, making this equally useful for teaching courses on pharmacology, drug metabolism or molecular toxicology.
Of particular interest, and unique to this volume is the inclusion of a wide range of additional xenobiotic compounds, including food supplements, herbal preparations, and agrochemicals.

About the Author
Pavel Anzenbacher heads the Department of Pharmacology at Palacky University, Olomouc (Czech Republic) and is vicepresident of the Czech Society of Clinical and Experimental Pharmacology and Toxicology. Having obtained his academic degrees from Charles University, Prague and from the Academy of Sciences of the Czech Republic he joined the Faculty of Medicine at Palacky University. His scientific contacts and stays have included e.g. the Princeton University, Vanderbilt University, Nashville, University of Connecticut, INSERM Montpellier, University of Lubeck, Technical University Berlin and Jagellonian University Cracow. Professor Anzenbacher has authored over 150 original scientific publications and has, among other honours, received the Fogarty Award of the USPHS.

Ulrich M. Zanger is deputy head of the Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart (Germany). A chemist by training, he began to work on drug metabolism at the Biocenter of the University of Basel, Switzerland, where he obtained a PhD
degree in biochemistry. He undertook postdoctoral studies at the Southwestern Medical Center at Dallas, Texas, before returning to Basel and later moving to Stuttgart. His major research interests are in human drug metabolizing cytochromes P450 and in basic and clinical aspects
of pharmacogenetics/genomics. Professor Zanger has authored more than 130 scientific articles and is lecturing in pharmacology and toxicology at the University of Tubingen.

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[Y382.Ebook] Download Ebook FUSE: Foresight-driven Understanding, Strategy and Execution: Move the Future, by Devadas Krishnadas

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Most existing businesses plan for a world that is straightforward and static. Unfortunately, the world does not work that way. In an increasingly complex and uncertain world, FUSE provides a way to tackle problems whilst incorporating uncertainty into our analyses.

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Written by renowned strategist and thinker Devadas Krishnadas, FUSE is a valuable tool for any business leader, manager or strategist.

• Sales Rank: #1635605 in eBooks
• Published on: 2015-09-01
• Released on: 2015-09-11
• Format: Kindle eBook

About the Author
Devadas Krishnadas is the founder and CEO of Future-Moves Group. Prior to this, Devadas played a leading role in developing Singapore's fiscal and social policy where he led efforts in long-term planning and strategic thinking.
He is the author of Sensing Singapore: Reflections in a Time of Change, and has been cited and published in international publications on foresight and strategy.

Most helpful customer reviews

0 of 1 people found the following review helpful.
Useful and practical framework
By KT
A very practical approach to guide how we can formulate and execute plans to deal with future uncertainties. The FUSE framework is weighted towards implementation and is suitsble for businesses that are facing short time to market cycles or rapidly changing external conditions which require rapid reviews of strategies. The FUSE framework helped my leadership team in developing plans to evolve the organisation's mission and identify new markets niches. Useful framework.

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[Q695.Ebook] Free PDF 12-Lead ECG: The Art Of Interpretation (Garcia, Introduction to 12-Lead ECG), by Tomas B. Garcia

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Welcome to the most comprehensive resource on 12-Lead ECG interpretation! This all-encompassing, four-color text, updated to the new Second Edition, is designed to make you a fully advanced interpreter of ECGs. Whether you are paramedic, nurse, nurse practitioner, physician assistant, medical student, or physician wanting to learn or brush up on your knowledge of electrocardiography, this book will meet your needs. 12-Lead ECG: The Art of Interpretation, Second Edition takes the complex subject of electrocardiography and presents it in a simple, innovative, 3-level approach. Level 1 provides basic information for those with minimal experience interpreting ECGs. Level 2 provides intermediate information for those with a basic understanding of the principles of electrocardiography. Level 3 provides advanced information for those with some mastery of the subject. The entire text is written in a friendly, easy-to-read tone. Additionally, the text contains real-life, full-size ECG strips that are integrated throughout the text and analyzed in conjunction with the concepts they illustrate.

• Sales Rank: #76267 in Books
• Brand: Brand: Jones n Bartlett Learning
• Published on: 2013-11-27
• Original language: English
• Number of items: 1
• Dimensions: 11.00" h x 8.50" w x 1.25" l, 3.35 pounds
• Binding: Paperback
• 680 pages

Features

• Used Book in Good Condition

About the Author
Garcia is board certified in both Internal Medicine and Emergency Medicine and has taught and practiced in the Emergency Departments of the Brigham and Women's Hospital/Harvard Medical School and Grady Memorial Hospital/Emory Medical School. Dr. Garcia currently teaches at the University of Miami School of Medicine and is establishing an Internet education site dedicated to emergency cardiac care and obesity-related issues at www.heartstuff.com.

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5 of 6 people found the following review helpful.
kindle VS paper book
By cc
can not xray in kindle
EKG sample number quoted can not reached easily, and has to flip several pages to view ,and search back to text
EKG are too small to view and not live size
paper book might be better

4 of 5 people found the following review helpful.
Awesome!
By Sam
This book is simply awesome. It explains the matter in a way that it sticks but never sounding like it is written for children or retards.
The book consists of three parts interwoven throughout the book. For beginners start with Blue level one and only do the parts marked Level One, once you mastered that basic understanding you return to the start of the book and go on with the parts marked Level Two with more in depth knowledge, after that return to the beginning again for part three, Level Three, in depth advanced knowledge is where its at at Level Three.
I utterly enjoy this book, I keep picking it up again to read another part en enjoy the notion that i actually get it!
It is rather an expensive book compared to so many other Cardio books out there and i have many of them at home but this one is worth every penny and i could have done without all the other books had i found this one earlier.
Go get it!

2 of 2 people found the following review helpful.
Best EKG book out there...student perspective
By Reviewer
If you want to really understand EKGs and be a complete boss whenever an EKG needs to be read, then get this book. I do not like the "review" style books even though sometimes they are necessary if you are short on time. But if you have the time, and really for a book as great as this you should make the time, then get this and truly understand EKGs. I hated the feeling of trepidation when seeing EKGs in the past. Now I see them and it's actually "fun" and I feel confident rather than apprehensive. 5/5

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Andrea Carandini's archaeological discoveries and controversial theories about ancient Rome have made international headlines over the past few decades. In this book, he presents his most important findings and ideas, including the argument that there really was a Romulus--a first king of Rome--who founded the city in the mid-eighth century BC, making it the world's first city-state, as well as its most influential. Rome: Day One makes a powerful and provocative case that Rome was established in a one-day ceremony, and that Rome's first day was also Western civilization's.

Historians tell us that there is no more reason to believe that Rome was actually established by Romulus than there is to believe that he was suckled by a she-wolf. But Carandini, drawing on his own excavations as well as historical and literary sources, argues that the core of Rome's founding myth is not purely mythical. In this illustrated account, he makes the case that a king whose name might have been Romulus founded Rome one April 21st in the mid-eighth century BC, most likely in a ceremony in which a white bull and cow pulled a plow to trace the position of a wall marking the blessed soil of the new city. This ceremony establishing the Palatine Wall, which Carandini discovered, inaugurated the political life of a city that, through its later empire, would influence much of the world.

Uncovering the birth of a city that gave birth to a world, Rome: Day One reveals as never before a truly epochal event.

• Sales Rank: #1117501 in Books
• Published on: 2011-07-25
• Original language: English
• Number of items: 1
• Dimensions: 7.32" h x 1.10" w x 5.72" l, .70 pounds
• Binding: Hardcover
• 184 pages

Review
"Tradition assigns [the founding of Rome] to the year 753 B.C., when Romulus--who, according to legend, was rescued from infanticide with his twin brother Remus and suckled by a she-wolf--erected the first walls of the so-called Roma Quadrata, or 'square Rome.' It has been a very long time since anyone took this account as an accurate historical description, but Carandini provocatively suggests that it might be more or less true."--Adam Kirsch, New Yorker

"It has been assumed generally that the traditional founding of Rome by twin brothers Romulus and Remus 28 centuries ago should be classified as myth. This provocative examination by a highly regarded but controversial archaeologist suggests, however, that the story contains more than a grain of truth . . . he marshals considerable evidence, written and archaeological, to bolster his claims, and his conclusions certainly are startling and exciting."--Jay Freeman, Booklist

"Carandini's gifts as an archaeologist are admired even by those who don't accept his interpretations and Rome: Day One is full of fascinating detail."--The Age

"'It's a bold book, but will not persuade all readers,' said ancient Rome Professor Christopher Smith of the British School at Rome. '[Still] no one in recent years has done more than Carandini to challenge our perceptions.'"--New York Post

"Researchers will be intrigued with Carandini's precise picture of early Rome and the fine illustrations."--Choice

"What makes Rome: Day One such an extraordinary book is not the erudite descriptions but the energetic style of prose. For a volume so packed with detail, it remains an astonishingly easy read. . . . This is a book written to bring those early days to the attention of anyone and everyone."--Caldrail, UNRV History

"[T]he book is interesting because it discusses a topic that is much eschewed by the modern historians as it treads on controversial religious aspects."--Vaidehi Nathan, Organiser

"Uncovering the birth of a city that gave birth to a world, Rome reveals as never before a truly epochal event."--World Book Industry

From the Inside Flap

"Dateline Rome, April 21, 753 BC. Andrea Carandini, archaeologist extraordinary, burrows down through thirteen meters of fill to hit pay dirt--Day 1 of Urbs Roma. What could be more exciting! History and archaeology rub shoulders with Freudian psychology as Carandini, a native of Rome, takes us on an enthralling guided tour through the material and written sources for the primal moment of the City that would create a World, our world. Urbi et Orbi, indeed."--Paul Cartledge, University of Cambridge

"A fascinating examination of how Rome began some twenty-eight centuries ago, written by an archaeologist whose many years of excavation have profoundly altered our understanding of the city and its history. Challenging, and often controversial, this book is a rewarding read both for the long-standing enthusiast and the newcomer to the subject, helping us to understand the development of the Roman state which went on to dominate so much of the known world."--Adrian Goldsworthy, author of Caesar: The Life of a Colossus

"Andrea Carandini's archaeological work in key areas of Rome will be fundamental to our understanding of the formative period of the city, and is part of the developing fascination with the beginnings of Rome. This translation brings the evidence, and Carandini's challenging interpretation, to a new audience."--Christopher Smith, director of the British School in Rome

From the Back Cover

"Dateline Rome, April 21, 753 BC. Andrea Carandini, archaeologist extraordinary, burrows down through thirteen meters of fill to hit pay dirt--Day 1 of Urbs Roma. What could be more exciting! History and archaeology rub shoulders with Freudian psychology as Carandini, a native of Rome, takes us on an enthralling guided tour through the material and written sources for the primal moment of the City that would create a World, our world. Urbi et Orbi, indeed."--Paul Cartledge, University of Cambridge

"A fascinating examination of how Rome began some twenty-eight centuries ago, written by an archaeologist whose many years of excavation have profoundly altered our understanding of the city and its history. Challenging, and often controversial, this book is a rewarding read both for the long-standing enthusiast and the newcomer to the subject, helping us to understand the development of the Roman state which went on to dominate so much of the known world."--Adrian Goldsworthy, author of Caesar: The Life of a Colossus

"Andrea Carandini's archaeological work in key areas of Rome will be fundamental to our understanding of the formative period of the city, and is part of the developing fascination with the beginnings of Rome. This translation brings the evidence, and Carandini's challenging interpretation, to a new audience."--Christopher Smith, director of the British School in Rome

Most helpful customer reviews

3 of 3 people found the following review helpful.
Caveat Lector!
By Remus
Caveat Lector! Carandini spins quite a tall tale in this book...but that's all it is—a work of fiction. Readers with a serious interest in early Rome are advised to read T.P Wiseman's review of this book in The Classical Journal ("Carandini's handsome little book offers no more than an enjoyable fantasy,") and Wiseman's longer expose of Carandini's other (Italian-language) books, "Reading Carandini," in The Journal of Roman Studies, which more closely examines Carandini's methodology (such as it is) and his personal motivations for advancing his idiosyncratic notions. Readers interested in rigorous history (as opposed to sheer fantasy) will find more substance in Cornell's The Beginnings of Rome and Wiseman's Remus: A Roman Myth.

4 of 5 people found the following review helpful.
A different sort of Roman scholarship
By Mario de Vivo
I gave "Rome, Day One" three stars with a heavy heart, because the book IS interesting. Having read anglo historians on ancient Rome, I have found it refreshing to be able to read an Italian archeological perspective and, besides, the often too dismissive historian view of Roman ancient tradition is unconvincing. Andrea Carandini believes that there is a structured core of truth about the Remus and Romulus story of the foundation of Rome, and he describes, with more detail than anybody else I've read, how the foundation could have happened. The illustrations are black, white and gray toned, but they are a banquet for the hungry eyes of everybody curious about how Rome really was like in the beginning. If other professional historians understood the power of illustration as Carandini does, their books would be so much better appreciated than they are!

The book has two aims: first, as stated above, to mix tradition and archeology in order to recreate the foundation of Rome, and the second is to present Rome, together with Greece, as distinct in terms of political organization from the ancient eastern states and empires, the democratic versus totalitarian roots of, respectively, the "West"and the "East" (indeed, Carandini extends this distinction to our own days in his "Conclusion", in a oversimplified manner).

The first objective is met finely, albeit with the same dismissiveness towards alternative views that historians show to the traditional account. I would like to know who thinks differently and why, and thus I probably would appreciate more Carandini's views. Instead, throughout the book, Carandini frequently reminds us that he has been excavating in the area for twenty years. Although this is not the only argument supporting his views, it feels like the number of years is very important in the matter, at least to him. It is and it is not, because one could have excavated for 40 years and end up finding little, while one luck digging season... Anyway, my point is that I would like to see more explaining and less bragging.

Another thing that bothered me is that he rarely mentions anybody else's archeological efforts, and he writes as if everything of importance have been found by him and his team. Maybe it is so, but maybe it isn't.

Finally, the author would have much helped his argument if he further clarified the comparison between early Roman foundation traditions and those that appeared after the Greek introduction of Troy, Aeneas, and other such characters in the story. He should have done it because the book is not for the specialist. This is very important because it would have supported his choice of sources for the traditional account.

Bottom line: if you like to read about the history of Rome, particularly early Rome, you must read this book, because it is so fascinating. Only be prepared for a different sort of scholarship than that of British and American historians.

4 of 5 people found the following review helpful.
Hard work if you're not an archaeologist or historian
By C. Watson
I'm star rating this item three because I suspect it is, in fact, an excellent piece of work for its intended audience of scholars, historians and archaelogists. It's not really fair for myself - a layman just interested in the history of Rome - to grade it according to my own lack of understanding, bust Amazon requires I add a rating, so three it is...

What I will say is this, the book is somewhat mis-marketed. Everything about its layout, cover art, blurb and design suggests that the reader is in for an engaging, argumentative, perhaps journalistic style laymans book. What it actually is, however, is a rather dense archaelogical thesis that I found somewhat slow-going and very difficult to comprehend. There's no narrative here, only a lot of challenging and dry scholarly description.

Here is a brief example:

"The King Augur and in(du)perator (Ennius), who had auxiliaries and a mounted guard, was potentissimus both with the priestly order - composed of the flamines of the divine triad and the five pontifices, in addition to the vestal virgins - and with respect to the Quirites gathering in the Comitia Calata and curiata where the king stated his ius, and from which bodies his army was formed."

If you had a hard time with that sentence then you'll have a hard time with the rest of the book.

As I stated I'm only entering this review as a warning for the lay readers who may be seeking something more narrative based and engaging. From a scholars perspective, though, it seems very good - lots of fascinating maps and diagrams of the dig sites and the corresponding foundation texts are well-sourced from primary sources such as Livy, Ovid and Plutarch. Actually the last thirty or so pages of the book is the appendix of the original texts from these sources and, in my opinion, made for a more engaging read than the book itself.

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[R950.Ebook] Download Ebook Solitary Confinement: Social Death and Its Afterlives, by Lisa Guenther

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Prolonged solitary confinement has become a widespread and standard practice in U.S. prisons—even though it consistently drives healthy prisoners insane, makes the mentally ill sicker, and, according to the testimony of prisoners, threatens to reduce life to a living death. In this profoundly important and original book, Lisa Guenther examines the death-in-life experience of solitary confinement in America from the early nineteenth century to today’s supermax prisons. Documenting how solitary confinement undermines prisoners’ sense of identity and their ability to understand the world, Guenther demonstrates the real effects of forcibly isolating a person for weeks, months, or years.

Drawing on the testimony of prisoners and the work of philosophers and social activists from Edmund Husserl and Maurice Merleau-Ponty to Frantz Fanon and Angela Davis, the author defines solitary confinement as a kind of social death. It argues that isolation exposes the relational structure of being by showing what happens when that structure is abused—when prisoners are deprived of the concrete relations with others on which our existence as sense-making creatures depends. Solitary confinement is beyond a form of racial or political violence; it is an assault on being.

A searing and unforgettable indictment, Solitary Confinement reveals what the devastation wrought by the torture of solitary confinement tells us about what it means to be human—and why humanity is so often destroyed when we separate prisoners from all other people.

• Sales Rank: #527071 in Books
• Published on: 2013-08-05
• Original language: English
• Number of items: 1
• Dimensions: 8.50" h x 1.10" w x 5.50" l, .90 pounds
• Binding: Paperback
• 368 pages

Review

In an unusually vigorous interrogation of philosophy and the social sciences, Lisa Guenther addresses one of humanity’s greatest inhumanities and its perversely long, extensive history in America. Guenther offers a compelling critique of solitary confinement, in the course of which she pushes phenomenology beyond its classical limits, revealing our inherent inter-subjectivity, our need for both interaction and anonymity, and the moral imperative that America end this cruel and barbaric form of punishment. An urgently needed, powerfully argued study of one of the nation’s gravest moral and socio-political failings.

—Orlando Patterson, Harvard University

About the Author

Lisa Guenther is associate professor of philosophy at Vanderbilt University and the author of The Gift of the Other: Levinas and the Politics of Reproduction. She facilitates a weekly discussion group at Riverbend Maximum Security Institution in Nashville, Tennessee.

Most helpful customer reviews

1 of 1 people found the following review helpful.
It is a very ditailed book. Presents a complete ...
By ulises tuduri
It is a very ditailed book. Presents a complete view point of the facts and consequences of our prison system.

2 of 5 people found the following review helpful.
Five Stars
By Mobridge-Pollock School District
Thank you.

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